Ground beef casseroles can be both delicious and nutritious, making them a perfect option for a wholesome, satisfying meal. By combining lean ground beef with vegetables, whole grains, and flavorful spices, these dishes deliver balanced nutrition without compromising on taste. Whether you prefer low-carb, protein-packed, or fiber-rich options, these casseroles are easy to prepare and full of hearty flavors. From classic comfort foods to creative, healthy twists, they offer a variety of nutrient-dense, family-friendly meals. Here are 17 flavorful ground beef casseroles that make dinnertime effortless, delicious, and nourishing—without sacrificing the joy of a great home-cooked meal!
1. Stuffed Pepper Casserole
Forget stuffing individual peppers—this casserole makes dinner way easier! It combines lean ground beef, brown rice, diced bell peppers, onions, and tomato sauce, all baked into one hearty dish. A sprinkle of cheddar cheese on top ties everything together, adding just the right amount of creaminess. The best part? You get all the flavors of classic stuffed peppers with half the effort. Want a low-carb option? Swap rice for cauliflower rice. Bake everything at 375°F for 25 minutes, and you’ll have a satisfying, veggie-packed meal the whole family will love.
2. Shepherd’s Pie Casserole
Classic comfort food just got a healthy makeover! Instead of traditional mashed potatoes, this version swaps in creamy mashed sweet potatoes for extra fiber and vitamins. Beneath the golden layer, you’ll find lean ground beef, carrots, peas, onions, and a savory gravy made with a touch of low-sodium broth and Worcestershire sauce.
The result? A deeply flavorful dish with a perfect balance of sweetness and savoriness. Bake at 400°F for 20 minutes, and watch the top turn beautifully golden. Serve it warm, and enjoy a cozy, satisfying meal that feels indulgent—but is actually good for you!
3. Beefy Green Bean Casserole
Who says green bean casserole is just for Thanksgiving? This hearty version packs lean ground beef, fresh green beans, mushrooms, and a homemade creamy sauce made with Greek yogurt instead of canned soup.
A little garlic and onion powder add depth, while Parmesan cheese sprinkled on top gives it a crispy, golden finish. It’s a one-pan wonder that’s high in protein and fiber but still delivers on that rich, comforting flavor. Simply bake at 375°F for 30 minutes, and you’ll have a nutritious meal that’s anything but boring.
4. Mexican Beef and Cornbread Casserole
Bold flavors meet wholesome ingredients in this Tex-Mex-inspired bake. Lean ground beef, black beans, fire-roasted tomatoes, and bell peppers create a hearty, protein-packed filling. Instead of traditional cornbread, this version uses a whole-grain cornmeal batter to add a light and slightly sweet topping.
A touch of cumin and chili powder brings warmth, while fresh cilantro and avocado slices add a refreshing contrast. Pop it in the oven at 375°F for 25 minutes, and you’ll have a deliciously balanced dish that satisfies both your comfort food cravings and your nutrition goals.
5. Spinach and Ricotta Ground Beef Casserole
This protein-packed, nutrient-rich casserole is the perfect blend of creamy and savory flavors. Instead of heavy cream or butter, this dish uses low-fat ricotta cheese to keep things light while still delivering a rich texture.
The lean ground beef is browned with garlic, onions, and a pinch of nutmeg, adding a subtle warmth that complements the flavors. Fresh baby spinach is mixed in for a boost of iron and fiber, creating a nutritious yet indulgent meal. Topped with a light sprinkle of Parmesan and mozzarella, this casserole is baked at 375°F for 25 minutes until golden and bubbly. Perfect for a comforting yet healthy weeknight dinner!
6. Cauliflower Rice and Parmesan Beef Casserole
This low-carb, high-protein casserole delivers rich, cheesy flavors without the heavy starches. Instead of traditional rice or pasta, it features cauliflower rice, keeping things light yet satisfying. The lean ground beef is sautéed with garlic, onions, and Italian seasoning, then mixed with the cauliflower rice and a creamy blend of Greek yogurt, Parmesan, and vegetable broth for a luscious texture. A sprinkle of almond flour and Parmesan on top creates a crispy, golden crust as it bakes at 375°F for 30 minutes. Each bite is packed with flavor, protein, and fiber, making this a perfect healthy comfort food option!
7. Whole Wheat Pasta Cheeseburger Casserole
Craving a cheeseburger but trying to stay on track? This casserole has all the flavor without the fast-food guilt. Lean ground beef, whole wheat pasta, diced tomatoes, and cheddar cheese come together in a creamy yet nutritious dish. Instead of heavy cream, Greek yogurt adds richness, while a little mustard and paprika give it that classic cheeseburger taste. Top with a sprinkle of low-fat mozzarella and bake at 350°F for 20 minutes. It’s comfort food with a healthy twist—and one the whole family will love!
8. Whole Grain & Low-Sugar Sloppy Joe Casserole
Ditch the sugary canned sauce and enjoy a homemade, wholesome twist on this classic casserole! It starts with lean ground beef, sautéed with diced onions, shredded carrots, and garlic, then simmered in a tangy tomato sauce made from apple cider vinegar, honey, smoked paprika, and crushed tomatoes for a rich, deep flavor. Baked at 375°F for 25 minutes, this dish is warm, slightly sweet, and incredibly satisfying—perfect for busy weeknights when you need a quick, nutritious comfort meal!
9. Zucchini Beef Casserole
Light, fresh, and packed with flavor, this zucchini beef casserole is perfect for those looking for a low-carb, high-protein meal. Thinly sliced zucchini rounds replace traditional starches, layered between seasoned lean ground beef, tomatoes, and onions.
A blend of Parmesan and mozzarella creates a light but satisfying cheesy topping. Baked at 375°F for 25 minutes, the zucchini softens just enough to absorb the savory flavors of the beef and spices, creating a dish that’s hearty yet refreshing. It’s a great option for those wanting a grain-free, veggie-packed meal that still feels indulgent.
10. Fiber-Rich Cornbread Casserole
This hearty, fiber-packed casserole is a perfect balance of savory, slightly sweet, and mildly spicy flavors. It starts with lean ground beef, sautéed with black beans, corn, bell peppers, onions, and garlic, all seasoned with chili powder and smoked paprika for a rich Tex-Mex taste.
A whole-grain cornbread batter is poured over the top, creating a fluffy, golden crust that complements the savory filling. Baked at 375°F for 25 minutes, it emerges warm, slightly crispy, and packed with protein and fiber. This one-pan wonder is easy to prep, incredibly satisfying, and perfect for busy weeknights!
11. Low-Carb Cheesesteak Casserole
Who says you need bread for a classic Philly cheesesteak? This low-carb version keeps all the flavor without the heavy carbs. Instead of a hoagie roll, this dish swaps in cauliflower rice as the base, making it light yet filling.
The casserole is loaded with lean ground beef, sautéed onions, bell peppers, and mushrooms, all seasoned with Worcestershire sauce and garlic powder for that signature savory taste. Topped with reduced-fat provolone or mozzarella, it bakes at 375°F for 20 minutes until bubbly and golden. Each bite delivers a cheesy, meaty, and guilt-free indulgence without compromising on taste!
12. Teriyaki Beef Casserole
Take your taste buds on a trip to Asia with this teriyaki-inspired beef casserole that’s both sweet and savory. It combines lean ground beef, brown rice, bell peppers, carrots, and snow peas, all tossed in a homemade teriyaki sauce made from low-sodium soy sauce, honey, garlic, and ginger.
A sprinkle of sesame seeds and sliced green onions adds the perfect finishing touch. Baked at 375°F for 20 minutes, this casserole is a flavorful, nutrient-packed meal that satisfies your takeout cravings—without the added sodium or processed ingredients. Serve with a side of steamed bok choy for an extra health boost!
13. Greek Moussaka Casserole
Moussaka is a beloved Greek dish, but it often comes with a heavy calorie load. This lighter version swaps fried eggplant for a roasted eggplant base, keeping it healthier without sacrificing flavor. The layers of lean ground beef, onions, and tomatoes are seasoned with cinnamon and oregano for an authentic Mediterranean touch. Instead of a heavy béchamel sauce, this casserole uses a Greek yogurt and egg mixture for creaminess. Baked at 375°F for 30 minutes, the top turns golden and delicious. This dish brings warmth, comfort, and a rich, savory taste—all while keeping things light and nutritious.
14. Broccoli and Cheddar Beef Casserole
This comforting casserole packs a powerful dose of protein and fiber with a delicious mix of lean ground beef, fresh broccoli florets, and a creamy cheddar cheese sauce. Instead of using a heavy cream base, this version lightens things up with Greek yogurt and low-fat cheddar, creating a rich and gooey texture without the guilt. Brown the beef with garlic and onions, mix it with steamed broccoli, and layer it into a baking dish. Sprinkle extra cheddar on top and bake at 375°F for 25 minutes until bubbly. The result? A wholesome, cheesy, and satisfying dinner!
15. Cabbage Roll Casserole
Skip the hassle of rolling individual cabbage leaves—this casserole simplifies the process while keeping all the flavor. Chopped green cabbage is layered with lean ground beef, brown rice, onions, and tomato sauce, creating a deconstructed version of the classic dish.
A touch of garlic, smoked paprika, and black pepper enhances the richness, while a slow bake at 375°F for 40 minutes allows all the flavors to meld beautifully. The result is a cozy, nutrient-packed meal high in fiber and protein. Garnish with fresh parsley for a bright, fresh finish, and enjoy a satisfying, homey dinner.
16. Spaghetti Squash & Beef Casserole
For a pasta-like experience without the carbs, this casserole swaps out noodles for roasted spaghetti squash, giving it a light yet satisfying texture. The strands of squash perfectly soak up the lean ground beef, marinara sauce, and garlic, creating a comforting and flavorful dish. Instead of heavy cheeses, a sprinkle of Parmesan and fresh basil keeps it light and fresh. Simply roast the spaghetti squash, mix it with the beef sauce, and bake at 375°F for 20 minutes. It’s a deliciously healthy way to enjoy an Italian-inspired meal while keeping it low-carb and packed with nutrients.
17. Southwest Black Bean & Beef Casserole
This bold and flavorful casserole is packed with lean ground beef, black beans, corn, tomatoes, and bell peppers, making it a fiber-rich, protein-loaded dish. Spiced with cumin, chili powder, and garlic, it brings a zesty kick that pairs perfectly with the hearty ingredients.
Instead of a heavy cheese layer, this dish is topped with sliced avocado and fresh cilantro for a refreshing contrast. Baked at 375°F for 25 minutes, it comes out warm, comforting, and full of Southwest flavors. Serve with a dollop of Greek yogurt instead of sour cream for extra protein and a lighter finish.
Leave a comment